PET is a nuclear-based modality used for decades as an important clinical tool to non-invasively image blood flow, cardiac tissue metabolism and receptor expression. PET has proven to be a superior technique for molecular imaging due to its accurate attenuation correction, higher spatial and temporal resolution, higher sensitivity, quantitative abilities coupled with lower radiation risk due to the use of short-lived isotopes.

Cardiac PET has greatly improved our understanding of human coronary vasomotor function in both physiological and pathophysiological conditions. Furthermore, it has been demonstrated that the diagnostic accuracy of myocardial perfusion imaging with PET for detecting obstructive coronary artery disease surpasses that of single photon emission CT (SPECT).


Use of Intravascular Ultrasound Imaging in Percutaneous Coronary Intervention to Treat Left Main Coronary Artery Disease


Interventional Cardiology Review 2017;12(1):8–12

Intravascular Photoacoustic Imaging of Vulnerable Atherosclerotic Plaque


Interventional Cardiology Review 2016;11(2):120–3

Choice of Intracoronary Imaging: When to Use Intravascular Ultrasound or Optical Coherence Tomography


Interventional Cardiology Review, 2016;11(1):11–6

Intravascular Ultrasound Versus Optical Coherence Tomography for Coronary Artery Imaging – Apples and Oranges?


Interventional Cardiology Review 2015;10(1):8–15